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Comment: ANOVA like approach of edgeR
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Gordon Smyth
52k
To identify common upregulated or downregulated genes, you would need to test for media condition contrasts for each cell type separately, …
Comment: DESeq2 sizefactors counfounded with biological treatment
by
Anna
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Hi James,
Apologies (re: posting in the wrong place).
Thank you so much for your response, that was exactly the help I needed.
Best,
A…
Comment: ANOVA like approach of edgeR
by
Talip
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10
I am comparing the expression patterns of different tissue cell lines (CellType) under five distinct media conditions (Status). Since the c…
Comment: Merge Replicates vs Mixed Model
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gabriel.hoffman
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160
It is almost always better to retain the full observed data, if the statistical software is able to model the repeated measures. This is a…
Comment: makeContrastsDream for Interaction
by
gabriel.hoffman
▴
160
The simplest way to handle contrasts with an interaction term is to create a new variable. Lets consider a simpler case with variables `Se…
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